abstract：OBJECTIVE:To provide a broader evidence summary to inform dietary guidelines of the effect of tree nuts on criteria of the metabolic syndrome (MetS). DESIGN:We conducted a systematic review and meta-analysis of the effect of tree nuts on criteria of the MetS. DATA SOURCES:We searched MEDLINE, EMBASE, CINAHL and the C...

journal_title：BMJ open

authors： Blanco Mejia S,Kendall CW,Viguiliouk E,Augustin LS,Ha V,Cozma AI,Mirrahimi A,Maroleanu A,Chiavaroli L,Leiter LA,de Souza RJ,Jenkins DJ,Sievenpiper JL

更新日期：2014-07-29 00:00:00

abstract：OBJECTIVE:Percutaneous pulmonary valve implantation is an alternative to open heart surgery in selected patients with pulmonary outflow tract disorder. The technique may reduce the number of open-chest surgeries in these patients. This study was conducted to understand how the patients and their next-of-kin experienced...

journal_title：BMJ open

authors： Andresen B,Andersen MH,Lindberg H,Døhlen G,Fosse E

更新日期：2014-07-29 00:00:00

abstract：INTRODUCTION:Reducing the time between the onset of the first symptoms of cancer and the first consultation with a doctor (patient delay) is essential to improve the vital prognosis and quality of life of patients. Longer patient delay is linked to the already known sociodemographic, socioeconomic, socioeducational, so...

journal_title：BMJ open

authors： Christophe V,Leroy T,Seillier M,Duthilleul C,Julieron M,Clisant S,Foncel J,Vallet F,Lefebvre JL

更新日期：2014-07-25 00:00:00

abstract：INTRODUCTION:Bone metastasis (BM) in patients with primary lung cancer poses a serious health problem. Numerous risk factors have been hypothesised to predict BM in these patients, but research studies are of mutable quality, and may not be of value in clinical evaluation. METHODS AND ANALYSIS:We will search a number ...

journal_title：BMJ open

authors： Niu YJ,Wen YT,Shen WW,Deng L,Liu LL,Zhang HL

更新日期：2014-07-24 00:00:00

abstract：OBJECTIVES:To further identify the single-nucleotide polymorphisms (SNPs) that contribute to the genetic susceptibility to sarcoidosis, we examined the potential association between sarcoidosis and 15 SNPs of the ANXA11 gene. DESIGN:A case-control study. SETTING:A tuberculosis unit in a hospital of the university in ...

journal_title：BMJ open

authors： Feng X,Zang S,Yang Y,Zhao S,Li Y,Gao X,Zhang L

更新日期：2014-07-23 00:00:00

abstract：OBJECTIVES:The optimal method of identifying people with chronic obstructive pulmonary disease (COPD) from electronic primary care records is not known. We assessed the accuracy of different approaches using the Clinical Practice Research Datalink, a UK electronic health record database. SETTING:951 participants regis...

journal_title：BMJ open

authors： Quint JK,Müllerova H,DiSantostefano RL,Forbes H,Eaton S,Hurst JR,Davis K,Smeeth L

更新日期：2014-07-23 00:00:00

abstract：OBJECTIVES:In the USA, there is little systematic evidence about the real-world trajectories of patient medical care after hospice enrolment. The objective of this study was to analyse predictors of the length of stay for hospice patients who were admitted to hospital in a retrospective analysis of the mandatorily repo...

journal_title：BMJ open

authors： Pathak EB,Wieten S,Djulbegovic B

更新日期：2014-07-22 00:00:00

abstract：OBJECTIVES:Anxiety disorders (ADs) are common after traumatic brain injury (TBI). However, the risk factors of new-onset ADs remain unclear. This study was aimed at evaluating the incidence and risk factors for new-onset ADs, including pre-existing hyperlipidaemia and three major comorbidities (diabetes mellitus, hyper...

journal_title：BMJ open

authors： Ho CH,Hsieh KY,Liang FW,Li CJ,Wang JJ,Chio CC,Chang CH,Kuo JR

更新日期：2014-07-17 00:00:00

abstract：OBJECTIVE:To determine whether valproate (VPA) monotherapy influences homocysteine metabolism in patients with epilepsy. DESIGN:Systematic review and meta-analysis. DATA SOURCES:We searched all articles in English through PubMed, Web of Science and EMBASE published up to August 2013 concerning the homocysteine levels...

journal_title：BMJ open

authors： Ni G,Qin J,Fang Z,Chen Y,Chen Z,Zhou J,Zhou L

更新日期：2014-07-16 00:00:00

abstract：OBJECTIVE:To explore the optimal content and design of a clinical trial of an end-of-life intervention for advanced heart disease with patients, carers and healthcare professionals. DESIGN:Qualitative interview and focus group study. SETTING:Community and hospital-based focus groups and interviews. PARTICIPANTS:Stab...

journal_title：BMJ open

authors： Denvir MA,Highet G,Robertson S,Cudmore S,Reid J,Ness A,Hogg K,Weir C,Murray S,Boyd K

更新日期：2014-07-14 00:00:00

abstract：OBJECTIVES:Prevalence estimates of multimorbidity vary widely due to inconsistent definitions and measurement methods. This study examines the independent effects on prevalence estimates of how 'disease entity' is defined-as a single chronic condition or chapters/domains in the International Classification of Primary C...

journal_title：BMJ open

authors： Harrison C,Britt H,Miller G,Henderson J

更新日期：2014-07-11 00:00:00

abstract：OBJECTIVE:This study examined the risk factors associated with failure of enhanced recovery protocol after major hepatobiliary and pancreatic (HBP) surgery. SETTING AND PARTICIPANTS:A retrospective cohort of 194 adult patients undergoing major HBP surgery at a university hospital in Hong Kong was followed up for 30 da...

journal_title：BMJ open

authors： Lee A,Chiu CH,Cho MW,Gomersall CD,Lee KF,Cheung YS,Lai PB

更新日期：2014-07-10 00:00:00

abstract：OBJECTIVE:To determine the relationship between biomarkers of exposure, disease and susceptibility, and early health effects and long-term diseases related to occupational manganese (Mn) exposure. DESIGN:Baseline survey of a longitudinal cohort study of workers in a ferromanganese refinery. PARTICIPANTS:A total of 18...

journal_title：BMJ open

authors： Lv Y,Zou Y,Liu J,Chen K,Huang D,Shen Y,Zhong Y,Liu Z,Jiang B,Li Q,Qing L,Zhang W,Chen L,Wang F,Xia B,Yang L,Yang X

更新日期：2014-07-03 00:00:00

abstract：INTRODUCTION:Governments in different countries have committed to better use of evidence from research in policy. Although many programmes are directed at assisting agencies to better use research, there have been few tests of the effectiveness of such programmes. This paper describes the protocol for SPIRIT (Supportin...

journal_title：BMJ open

authors： CIPHER Investigators.

更新日期：2014-07-01 00:00:00

abstract：INTRODUCTION:Desert dust is estimated to constitute about 35% of aerosol in the troposphere. Desertification, climatic variability and global warming all can contribute to increased dust formation. This study aims to examine possible health effects of desert dust exposure on pregnant women and their children. The purpo...

journal_title：BMJ open

authors： Kanatani KT,Adachi Y,Sugimoto N,Noma H,Onishi K,Hamazaki K,Takahashi Y,Ito I,Egawa M,Sato K,Go T,Kurozawa Y,Inadera H,Konishi I,Nakayama T,Japan Environment & Children's Study Group.

更新日期：2014-06-23 00:00:00

abstract：OBJECTIVE:To systematically review the literature for evidence of smoking and alcohol intake as independent risk factors for invasive pneumococcal disease (IPD). DESIGN:Systematic review. METHODS:MEDLINE (1946-May 2012) and EMBASE (1947-May 2012) were searched for studies investigating alcohol or smoking as risk fact...

journal_title：BMJ open

authors： Cruickshank HC,Jefferies JM,Clarke SC

更新日期：2014-06-20 00:00:00

abstract：OBJECTIVE:To assess the representativeness of the Heart Protection Study (HPS) and the Collaborative Atorvastatin Diabetes Study (CARDS) for incident statin users. DESIGN:A population-based analysis with linked register data. SETTING:Finland. POPULATION:56 963 patients with diabetes initiating statin use from 2005 t...

journal_title：BMJ open

authors： Ruokoniemi P,Sund R,Arffman M,Helin-Salmivaara A,Huupponen R,Keskimäki I,Vehko T,Korhonen MJ

更新日期：2014-06-19 00:00:00

abstract：OBJECTIVE:Maternal morbidity, either pregnancy related or pre-existent, can become life threatening and of such severity as to warrant termination of pregnancy (TOP). In this situation, chances of fetal survival are usually poor, either because of low gestational age and/or because of the fetal effects of the maternal ...

journal_title：BMJ open

authors： van Eerden L,Zeeman GG,Page-Christiaens GC,Vandenbussche F,Oei SG,Scheepers HC,van Eyck J,Middeldorp JM,Pajkrt E,Duvekot JJ,de Groot CJ,Bolte AC

更新日期：2014-06-17 00:00:00

abstract：OBJECTIVE:To assess the barriers to uptake of eye care services among those with avoidable impairment in the population aged ≥40 years in the South Indian state of Andhra Pradesh. DESIGN:Cross-sectional study. SETTING:Community setting. PARTICIPANTS:Of 7800 participants recruited from one urban and two rural locatio...

journal_title：BMJ open

authors： Marmamula S,Khanna RC,Shekhar K,Rao GN

更新日期：2014-06-12 00:00:00

abstract：INTRODUCTION:Dextro-transposition of the great arteries (d-TGA) is a life-threatening congenital health defect that requires rapid surgery. The most widely used approach is the arterial switch operation (ASO) developed by Jatene in the 1970s. The first set of children who received this intervention are now adults. The ...

journal_title：BMJ open

authors： Mbuagbaw L,Forlemu-Kamwa D,Chu A,Thabane L,Dillenberg R

更新日期：2014-06-11 00:00:00

abstract：OBJECTIVES:To evaluate glycaemic durability with dipeptidyl peptidase-4 (DPP-4) inhibitors in type 2 diabetes. DESIGN:A systematic review and meta-analysis of long-term randomised trials of DPP-4 inhibitors on haemoglobin A1c (HbA1c) was conducted. Electronic searches were carried out on the following databases: MEDLI...

journal_title：BMJ open

authors： Esposito K,Chiodini P,Maiorino MI,Bellastella G,Capuano A,Giugliano D

更新日期：2014-06-10 00:00:00

abstract：OBJECTIVE:It is well documented that both work stress and work motivation are key determinants of job satisfaction. The aim of this study was to examine levels of work stress and motivation and their contribution to job satisfaction among community health workers in Heilongjiang Province, China. DESIGN:Cross-sectional...

journal_title：BMJ open

authors： Li L,Hu H,Zhou H,He C,Fan L,Liu X,Zhang Z,Li H,Sun T

更新日期：2014-06-05 00:00:00

abstract：OBJECTIVES:The illicit use of anabolic steroids among the gym population continues to rise, along with the number of steroid using clients attending harm reduction services in the UK. This presents serious challenges to public health. Study objectives were to account for the experiences of anabolic steroid users and in...

journal_title：BMJ open

authors： Kimergård A,McVeigh J

更新日期：2014-06-04 00:00:00

abstract：OBJECTIVE:The proper use of safety measures by welders is an important way of preventing and/or reducing a variety of health hazards that they are exposed to during welding. There is a lack of knowledge about hazards and personal protective equipments (PPEs) and the use of PPE among the welders in Nepal is limited. We ...

journal_title：BMJ open

authors： Budhathoki SS,Singh SB,Sagtani RA,Niraula SR,Pokharel PK

更新日期：2014-06-02 00:00:00

abstract：INTRODUCTION:In the context of a population that is growing older, and a number of high-profile scandals about care standards in hospital and community settings, having a skilled and knowledgeable workforce caring for older people is an ethical and policy imperative. Support workers make up the majority of the workforc...

journal_title：BMJ open

authors： Rycroft-Malone J,Burton C,Hall B,McCormack B,Nutley S,Seddon D,Williams L

更新日期：2014-05-30 00:00:00

abstract：BACKGROUND:Female injection drug users (IDUs) may report differences in injection behaviours that put them at greater risk for hepatitis C virus (HCV). Few studies have examined these in association with HCV incidence. METHODS:Longitudinal data from a cohort of 417 HCV-uninfected IDU aged 30 or younger were analysed. ...

journal_title：BMJ open

authors： Tracy D,Hahn JA,Fuller Lewis C,Evans J,Briceño A,Morris MD,Lum PJ,Page K

更新日期：2014-05-29 00:00:00

abstract：OBJECTIVES:To investigate the association between psychosocial, sociodemographic and material determinants of positive mental health in Europe. DESIGN:Cross-sectional analysis of survey data. SETTING:34 European countries. PARTICIPANTS:Representative Europe-wide sample consisting of 21 066 men and 22 569 women aged ...

journal_title：BMJ open

authors： Dreger S,Buck C,Bolte G

更新日期：2014-05-28 00:00:00

abstract：OBJECTIVES:To assess whether Portuguese family physicians perform preventive health services in accordance with scientific evidence, based on the recommendations of the United States Preventive Services Task Force (USPSTF). DESIGN:Cross-sectional study. SETTING:Primary healthcare, Portuguese National Health Service. ...

journal_title：BMJ open

authors： Martins C,Azevedo LF,Santos C,Sá L,Santos P,Couto M,Pereira A,Hespanhol A

更新日期：2014-05-26 00:00:00

abstract：OBJECTIVES:To conduct a systematic review to identify studies that describe factors and interventions at primary care practice level that impact on levels of utilisation of unscheduled secondary care. SETTING:Observational studies at primary care practice level. PARTICIPANTS:Studies included people of any age of eith...

journal_title：BMJ open

authors： Huntley A,Lasserson D,Wye L,Morris R,Checkland K,England H,Salisbury C,Purdy S

更新日期：2014-05-23 00:00:00

abstract：OBJECTIVE:Conduct a global situational analysis to identify the current facilitators and barriers to improving quality of care (QoC) for pregnant women, newborns and children. STUDY DESIGN:Metareview of published and unpublished systematic reviews and meta-analyses conducted between January 2000 and March 2013 in any ...

journal_title：BMJ open

authors： Nair M,Yoshida S,Lambrechts T,Boschi-Pinto C,Bose K,Mason EM,Mathai M

更新日期：2014-05-22 00:00:00

abstract：INTRODUCTION:The study 'Mental healthcare provision for adults with intellectual disability and a mental disorder' (MEMENTA) is a cross-sectional epidemiological study carried out in three different regions of Germany. Its main aim is to assess the prevalence of mental disorders in adults with intellectual disability (...

journal_title：BMJ open

authors： Koch A,Vogel A,Holzmann M,Pfennig A,Salize HJ,Puschner B,Schützwohl M

更新日期：2014-05-20 00:00:00

abstract：OBJECTIVES:To evaluate patient experiences of specific aspects of haemodialysis care across several countries. DESIGN:Cross-sectional survey using the Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) questionnaire. SETTING:Haemodialysis clinics within a single provider in Europe and South A...

journal_title：BMJ open

authors： Palmer SC,de Berardis G,Craig JC,Tong A,Tonelli M,Pellegrini F,Ruospo M,Hegbrant J,Wollheim C,Celia E,Gelfman R,Ferrari JN,Törok M,Murgo M,Leal M,Bednarek-Skublewska A,Dulawa J,Strippoli GF

更新日期：2014-05-19 00:00:00

abstract：OBJECTIVE:To compare the effects on balance and walking of three models of stroke rehabilitation: early supported discharge with rehabilitation in a day unit or at home, and traditional uncoordinated treatment (control). DESIGN:Group comparison study within a randomised controlled trial. SETTING:Hospital stroke unit ...

journal_title：BMJ open

authors： Gjelsvik BE,Hofstad H,Smedal T,Eide GE,Næss H,Skouen JS,Frisk B,Daltveit S,Strand LI

更新日期：2014-05-14 00:00:00

abstract：OBJECTIVES:To examine the damage location distribution of five main body region injuries of maximum abbreviated injury score (MAIS) 3-6 injured occupants for nearside struck vehicle in front-to-side impact crashes. DESIGN AND SETTING:MAIS 3-6 injured occupants information was extracted from the US-National Automotive ...

journal_title：BMJ open

authors： Tang Y,Cao L,Kan S

更新日期：2014-05-08 00:00:00

abstract：OBJECTIVE:New electronic devices offer an opportunity within routine primary care settings for improving the detection of atrial fibrillation (AF), which is a common cardiac arrhythmia and a modifiable risk factor for stroke. We aimed to assess the performance of a modified blood pressure (BP) monitor and two single-le...

journal_title：BMJ open

authors： Kearley K,Selwood M,Van den Bruel A,Thompson M,Mant D,Hobbs FR,Fitzmaurice D,Heneghan C

更新日期：2014-05-02 00:00:00

abstract：OBJECTIVE:To evaluate the effects of intravenous fluid bolus compared to maintenance intravenous fluids alone as part of immediate emergency care in children with severe febrile illness and signs of impaired circulation in low-income settings. DESIGN:Systematic review of randomised controlled trials (RCTs), and observ...

journal_title：BMJ open

authors： Opiyo N,Molyneux E,Sinclair D,Garner P,English M

更新日期：2014-04-30 00:00:00

abstract：INTRODUCTION:This review aims to evaluate the efficacy of acupuncture in the treatment of chronic obstructive pulmonary disease (COPD). METHODS AND ANALYSIS:14 databases will be searched from their inception. These include PubMed, AMED, EMBASE, the Cochrane Library, seven Korean medical databases (Korean Studies Infor...

journal_title：BMJ open

authors： Choi TY,Jun JH,Choi JY,Kim JI,Lee MS,Ernst E

更新日期：2014-04-28 00:00:00

abstract：INTRODUCTION:Monitoring and reduction of aversive tension is a core issue in dialectical behaviour therapy of patients. It has been shown that aversive tension is increased in adult borderline personality disorder and is linked to low emotion labelling ability. However, until now there is no documented evidence that pa...

journal_title：BMJ open

authors： Kolar DR,Bürger A,Hammerle F,Jenetzky E

更新日期：2014-04-23 00:00:00

abstract：OBJECTIVE:Legislation to safeguard children from maltreatment by carers or violence by others was advanced in England and Scotland around 2004-2005 and resulted in different policies and services. We examined whether subsequent trends in injury admissions to hospital related to maltreatment or violence varied between t...

journal_title：BMJ open

authors： Gonzalez-Izquierdo A,Cortina-Borja M,Woodman J,Mok J,McGhee J,Taylor J,Parkin C,Gilbert R

更新日期：2014-04-22 00:00:00

abstract：OBJECTIVE:Previous systematic reviews were not restricted to either primary or secondary prevention trials, this study aimed to investigate the effects of reduced and/or modified fat diets and dietary fatty acids on all-cause mortality, cardiovascular mortality and cardiovascular events in participants with established...

journal_title：BMJ open

authors： Schwingshackl L,Hoffmann G

更新日期：2014-04-19 00:00:00